A sequence that directs transcriptional initiation in yeast
نویسندگان
چکیده
منابع مشابه
The yeast FACT complex has a role in transcriptional initiation.
A crucial step in eukaryotic transcriptional initiation is recognition of the promoter TATA by the TATA-binding protein (TBP), which then allows TFIIA and TFIIB to be recruited. However, nucleosomes block the interaction between TBP and DNA. We show that the yeast FACT complex (yFACT) promotes TBP binding to a TATA box in chromatin both in vivo and in vitro. The SPT16 gene encodes a subunit of ...
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ژورنال
عنوان ژورنال: Current Genetics
سال: 1990
ISSN: 0172-8083,1432-0983
DOI: 10.1007/bf00312597